I am trying to master a project, which would involve microorganisms for the production of unique “matter.” The setup ideally should not require bsl1 for its production. Marc proposed to work on the production of chymosin, which does not need bsl1 in Switzerland (at least). Chymosin could be interesting as it has already some history behind hackteria, and is widely used in the industry. For having the produced matter “unique” I could imagine using point mutations. But perhaps there are also other, more elegant ways to come up with the expected results. Any comments?